Current views on cervical intraepithelial neoplasia.

نویسندگان

  • M C Anderson
  • C L Brown
  • C H Buckley
  • H Fox
  • D Jenkins
  • D G Lowe
  • B T Manners
  • D H Melcher
  • A J Robertson
  • M Wells
چکیده

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Utility of P16/INK4a and Ki-67 in Preneoplasticand Neoplastic Lesions of Cervix

Background and Objective: The currentstudy aimed at investigating the histomorphological spectrum of cervical intraepithelial and invasive lesions assessing the diagnostic significance of P16/INK4a and Ki-67 in such lesions, andcorrelatingP16/INK4a and Ki-67 immunoexpression with histologic type and grade.Methods: A total of 60 cases were selectedcomprisi...

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  Abstract   Background & Aims: Combined oral contraceptive pills (OCP) provide highly effective birth control. Studies have indicated that the risk for dysplasia and carcinoma insitu of the uterine cervix increases with the use of oral contraception for more than 1 year. Invasive cervical cancer may increase after 5 years of us reaching a 2- fold increase after 10 years. But conclusions regard...

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Detection of persistent cervical carcinogenic human papillomavirus (HPV) DNA is used as a marker for cervical cancer risk in clinical trials. The authors performed a systematic review and meta-analysis of the association between persistent HPV DNA and high-grade cervical intraepithelial neoplasia (CIN2-3), high-grade squamous intraepithelial lesions (HSIL), and invasive cervical cancer (togethe...

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عنوان ژورنال:
  • Journal of clinical pathology

دوره 44 12  شماره 

صفحات  -

تاریخ انتشار 1991